Analysis of Urine Podocalyxin in Type 2 Diabetes Mellitus Subjects With and Without Diabetic Nephropathy

Type 2 diabetes mellitus is the most common cause of diabetes, consist from about 85% cases. Diabetic nephropathy a complication in kidneys which can end up as kidney failure. Podocalyxin (PDX) protein expressed podocytes that involved various cancers, and also essential for development. The research design was carried out using observational cross-sectional analytic methods with total participants 25 DM diabetic without purposive probability sampling technique. This conducted at Endocrine Polyclinic, Clinical Pathology Laboratory, Hasanuddin University Medical Research Center (HUM-RC) Hospital, Makassar. results showed urinary PDX level subjects were 1.160 ng/mL 0.167 (p<0.001), urine albumin/creatinine ratio (ACR) 644.74 mg/ g 10.071 mg/g (p<0.001) correlation test ACR (r=0.510; p=0.001). study concluded there significant difference between nephropathy, levels relationship nephropathy.